Myrcia bella Leaf Extract Presents Hypoglycemic Activity via PI3k/Akt Insulin Signaling Pathway

Figure 7

Protein expression in liver. Western blot analysis of IRS-1 (a), PI3-K(b), and AKT (c) from liver of control and diabetic mice treated with saline (CTL SAL and STZ SAL) or with 600 mg/Kg of the crude extract of M. bella during 14 days (CTL EXT and STZ EXT). p-IRS-1, p-PI3-K, and P-AKT are the phosphorylated forms of the respective proteins. Data are Means±SEM. ∗ versus STZ SAL, @ versus CTL SAL, & versus CTL EXT, 𝑛=6, 𝑃<0.05. ANOVA followed by Tukey’s posttest.

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