Table 4: Abnormal clinical findings at the start of the study and after 24 weeks of treatment.

Treatment Placebo value
Week 0Week 24Week 0Week 24Weeks 0 and 24

SBP ≥ 140 or DBP ≥ 90 mmHg*13 (35.1)13 (33.3)12 (32.4)13 (33.3)0.764, 0.933
Fasting glucose ≥ 126 mg/dL* 6 (16.2) 8 (21.6) 5 (12.8)10 (25.6)0.674, 0.680
AST or ALT ≥ 1.5 × upper limit of normal**0 (0.0)1 (2.7)0 (0.0) 2 (5.1)NA, 0.520
Creatinine ≥ 1.5 mg/dL**0 (0.0)1 (2.7)0 (0.0)0 (0.0)NA, 0.487

AST: aspartate transaminase; ALT: alanine transaminase; DBP: diastolic blood pressure; SBP: systolic blood pressure.
Data are expressed as frequency (percent). *Chi-square test or **Fisher’s exact test.