Effect of Huanglian Jiedu Decoction on Thoracic Aorta Gene Expression in Spontaneous Hypertensive Rats

Table 1

Downregulated genes in hypertension rats.

Gene	Abbr.	Gene Id	Chro.	FC	𝑃
DRABUB01 rat DRG library Rattus norvegicus cDNA clone DRABUB01 5′	—	NA	9	0.097	3.86𝐸−03
Similar to RIKEN cDNA 1700001F09 (LOC289957)	—	NA	15	0.092	9.47𝐸−05
Mitochondrial ribosomal protein S2	Mrps2	362094	3	0.081	6.49𝐸−03
Q99LR9_MOUSE (Q99LR9) Riok3 protein (fragment), partial (13%)	—	NA	18	0.079	6.79𝐸−04
AGENCOURT_26625193 NIH_MGC_253 Rattus norvegicus cDNA clone IMAGE:7304073 5′	—	NA	5	0.054	6.58𝐸−03
Similar to 60S ribosomal protein L19 (LOC316856)	—	NA	Un	0.053	1.40𝐸−04
Solute carrier family 4 (anion exchanger), member 1	Slc4a1	24779	10	0.051	8.24𝐸−03
Cell division cycle 25 homolog A (S. pombe)	Cdc25a	171102	8	0.039	6.88𝐸−04
Synuclein, alpha (non-A4 component of amyloid precursor)	Snca	29219	4	0.029	6.00𝐸−03
Unknown	—	NA	7	0.028	2.12𝐸−04
Coproporphyrinogen oxidase	Cpox	304024	11	0.021	2.11𝐸−06
AGENCOURT_70342463 NIH_MGC_368 Rattus norvegicus cDNA clone IMAGE:8376762 5′	—	NA	1	0.013	9.98𝐸−03
Q8FIR6_ECOL6 (Q8FIR6) cytochrome b561 homolog 2, partial (5%)	—	NA	9	0.009	2.05𝐸−04
UI-R-C3-sf-g-04-0-UI	—	NA	1	0.007	6.28𝐸−03

Note. Abbr.: gene abbreviation, Chro.: chromosome, Gene Id represents the identity (ID) of the gene in GenBank; FC = SHR model group gene expression level/normotensive WKY control group expression level. “—/NA/Un” indicates unknown.