Effect of Huanglian Jiedu Decoction on Thoracic Aorta Gene Expression in Spontaneous Hypertensive Rats

Table 2

Upregulated genes (model versus control).

Gene	Abbr.	Gene Id	Chro.	FC	𝑃
Bone gamma-carboxyglutamate (gla) protein	Bglap	25295	2	61.402	1.96𝐸−03
Uncharacterized protein	—	NA	2	25.856	1.96𝐸−05
Unknown	—	NA	13	24.949	9.99𝐸−03
Cellular retinoic acid binding protein 2	Crabp2	29563	2	20.657	4.73𝐸−03
Major histocompatibility complex, assembled from 40 BACs, strain Brown Norway (BN/ssNHsd), RT1n haplotype; segment 2/11	—	NA	20	19.648	1.52𝐸−03
V-set domain containing T cell activation inhibitor 1	Vtcn1	295322	2	18.951	1.15𝐸−03
Interferon-induced protein with tetratricopeptide repeats 1	Ifit1	56824	1	17.991	1.51𝐸−04
Unknown	—	NA	10	13.875	5.54𝐸−03
Uncharacterized protein	—	NA	1	13.621	5.06𝐸−04
Similar to SMAD-interacting zinc finger protein 2	LOC679126	679126		13.572	8.21𝐸−05
Transient receptor potential cation channel, subfamily C, member 4	Trpc4	84494	2	13.374	8.20𝐸−04
Q3X0T1_9ACTN (Q3X0T1) 60 kDa innermembrane protein, partial (6%)	—	NA	19	12.417	4.35𝐸−03
CJ032_MOUSE (Q9CRC6) protein C10orf32 homolog, partial (15%)	—	NA	1	11.726	8.63𝐸−04
TL0ACA45YL24	—	NA	X	11.407	1.80𝐸−03

Note. Abbr.: gene abbreviation, Chro.: chromosome, Gene Id represents the identity (ID) of the gene in GenBank; FC = SHR model group gene expression level/normotensive WKY control group expression level. “—/NA/Un” indicates unknown.