Effect of Huanglian Jiedu Decoction on Thoracic Aorta Gene Expression in Spontaneous Hypertensive Rats

Table 5

Functional category of HJD-induced gene change profiles.

GO Id	Term	Hit genes	𝑃
GO:0002376	Immune system process
GO:0002520	Immune system development	10	0.0001
GO:0045321	Leukocyte activation	12	0.0001
GO:0002682	Regulation of immune system process	12	0.0001
GO:0006955	Immune response	10	0.0003
GO:0002684	Positive regulation of immune system process	7	0.0006
GO:0045058	T cell selection	2	0.0046
GO:0002253	Activation of immune response	3	0.026
GO:0009987	Cellular process
GO:0001775	Cell activation	13	0.0001
GO:0008283	Cell proliferation	15	0.0001
GO:0048522	Positive regulation of cellular process	22	0.0002
GO:0008219	Cell death	13	0.0016
GO:0048523	Negative regulation of cellular process	16	0.0086
GO:0016043	Cellular component organization	19	0.0181
GO:0007049	Cell cycle	7	0.0453
GO:0008152	Metabolic process
GO:0009058	Biosynthetic process	28	0.0005
GO:0009893	Positive regulation of metabolic process	11	0.0361
GO:0006807	Nitrogen compound metabolic process	5	0.0413
GO:0019748	Secondary metabolic process	2	0.0423
GO:0032502	Developmental process
GO:0050793	Regulation of developmental process	17	0.0008
GO:0051093	Negative regulation of developmental process	10	0.0026
GO:0048856	Anatomical structure development	21	0.0086
GO:0009790	Embryonic development	8	0.0154
GO:0007275	Multicellular organismal development	20	0.0249
GO:0001503	Ossification	4	0.0251
GO:0009653	Anatomical structure morphogenesis	12	0.0409
GO:0016265	Death
GO:0008219	Cell death	13	0.0016
GO:0032501	Multicellular organismal process
GO:0001816	Cytokine production	7	0.0003
GO:0051240	Positive regulation of multicellular organismal process	7	0.0017
GO:0051239	Regulation of multicellular organismal process	14	0.0021
GO:0007275	Multicellular organismal development	20	0.0249
GO:0050896	Response to stimulus
GO:0006955	Immune response	10	0.0003
GO:0009605	Response to external stimulus	11	0.0084
GO:0009607	Response to biotic stimulus	6	0.0201
GO:0048584	Positive regulation of response to stimulus	5	0.0209
GO:0048585	Negative regulation of response to stimulus	3	0.0445
GO:0050789	Regulation of biological process
GO:0002682	Regulation of immune system process	12	0.0001
GO:0048518	Positive regulation of biological process	24	0.0001
GO:0050793	Regulation of developmental process	17	0.0008
GO:0051239	Regulation of multicellular organismal process	14	0.0021
GO:0048519	Negative regulation of biological process	18	0.0045
GO:0032844	Regulation of homeostatic process	3	0.045
GO:0048518	Positive regulation of biological process	24	0.0001
GO:0048519	Negative regulation of biological process	18	0.0045
GO:0010926	Anatomical structure formation	12	0.0254