Evidence-Based Complementary and Alternative Medicine

Research Article

Effect of Huanglian Jiedu Decoction on Thoracic Aorta Gene Expression in Spontaneous Hypertensive Rats

Table 6

Hypertension altered genes in 22 KEGG pathways.
KEGG pathwayHit genes
Olfactory transduction 290
Neuroactive ligand-receptor interaction 130.0002
Cytokine-cytokine receptor interaction 100.0009
Focal adhesion 90.0009
Tight junction 60.0061
RIG-I-like receptor signaling pathway 40.0081
Ether lipid metabolism 30.0083
Calcium signaling pathway 70.0086
Leishmania infection 40.0089
Amyotrophic lateral sclerosis (ALS) 40.0113
Arrhythmogenic right ventricular cardiomyopathy (ARVC) 40.014
ABC transporters 30.0171
Aldosterone-regulated sodium reabsorption 30.0213
Hypertrophic cardiomyopathy (HCM) 40.0231
Dilated cardiomyopathy 40.0247
Glycosphingolipid biosynthesis—ganglio series 20.0265
Glutathione metabolism 30.0284
Apoptosis 40.032
Wnt signaling pathway 50.0324
Natural killer cell mediated cytotoxicity 50.0339
Maturity onset diabetes of the young 20.0415
MAPK signaling pathway 70.047