Xilei San Ameliorates Experimental Colitis in Rats by Selectively Degrading Proinflammatory Mediators and Promoting Mucosal Repair

<table>XLS stimulated enterocyte proliferation in DSS-treated rats. (a) Water + saline; (b) water + XLS; (c) DSS + saline; and (d) DSS + XLS (immunohistochemistry, ×40 and ×400 original magnification). (e) Cell proliferation was evaluated by LI, representative of the immunoreactivity of Ki-67 in colon sections. Numbers in brackets represent sample numbers of each group. <svg height="17.825001" id="M140" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 76.137497 17.825001" width="76.137497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus water + saline, <svg height="20.1875" id="M141" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 79.087502 20.1875" width="79.087502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,-0,0,-.017,20.438,17.238)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg> versus water + saline, and <svg height="20.612499" id="M142" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 67.875 20.612499" width="67.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus DSS + XLS.</table>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Xilei San Ameliorates Experimental Colitis in Rats by Selectively Degrading Proinflammatory Mediators and Promoting Mucosal Repair 