Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 1

Research Article

Chemical Profiling of an Antimigraine Herbal Preparation, Tianshu Capsule, Based on the Combination of HPLC, LC-DAD-MSn, and LC-DAD-ESI-IT-TOF/MS Analyses

Table 1

Retention time ( ), UV, and LC-MS data of the identified compounds in Tianshu Capsule and related crude materials.

Number /minUV /nmMW[M − H][M + H]+[M + NH4]+[M + Na]+[2M + Na]+[M + HCOO]TianmaChuanxiongIdentified compounds

25.403221, 276286304331+Gastrodin
37.736230, 283126127144149+5-HMF
415.579225460459478483+Parishin E/G
520.691221, 272728727746751+Parishin B
622.220221, 274728727746751+Parishin C
825.080218242241243265507+3-Butyl-3,6,7-trihydroxy-4,5,6,7
-tetrahydrophthalide
925.567220, 236, 323194193195217++ferulic acid
1027.529220, 330226227249475+Senkyunolide J/N
1130.667280224225247471+4,5-Dihydro-3,1′-dihydroxy-3
-butylphthalide
1332.436275206205207+4-hydroxyl-3-butylphthalide
1434.299325396397++unidentified
1638.635220, 270222221223245+Senkyunolide D or
4,7-dihydroxy-3-butylidenephthalide
1739.502230, 310206205207229435+ -6,7-Epoxyligustilide
1839.898280208207209231439+Senkyunolide K/G
1941.465220206205207229435+Senkyunolide F
2042.332220, 240, 325192193215407++Senkyunolide A
2142.956226, 280190191208213403+Butylphthalide
2243.717218, 270204203205227431249+Senkyunolide C
2344.147210, 285, 330204203205227431249+Senkyunolide E
2444.949220, 270, 330194195217411+Cnidilide
2645.831205, 280, 328190191213403+Ligustilide
2746.394220194195217411+Neocnidilide
2846.653210, 275, 330188189206211399+3-Butylidenephthalide
2947.231225, 280, 310380381398403+Riligustilide
3050.042276382383399405+Senkyunolide P
3150.476220, 280380381398403+3′,6,8′,3a-Biligustilide
3250.970220, 280380381398403+Tokinolide B
3351.065230, 279382383400405+Unidentified
3451.962220, 275380381403+ Levistolide A
3552.267220, 285380381+3′ -3,3′a,8,6′a-Biligustilide
3652.693220, 280278279301579+Senkyunolide M
3753.134220, 280278279301579+Senkyunolide Q
3853.852225, 278382383400405383+Unidentified