Centella asiatica Attenuates Diabetes Induced Hippocampal Changes in Experimental Diabetic Rats

Table 1

Effect of C. asiatica leaf aqueous extract on FBG levels and hippocampal tissue somatic index in experimental diabetic rats.

Parameters	Normal	Diabetic	Diabetic
			100 mg/kg b.w; C. asiatica	200 mg/kg b.w; C. asiatica	600 𝜇g/kg b.w; glibenclamide
0th day blood glucose levels	94.38 ± 7.27	438.27*  ± 9.83	436.81^ns  ± 7.69	437.68^ns  ± 9.63	436.65^ns  ± 9.76
28th day blood glucose levels	98.64 ± 8.67	432.16*  ± 7.16	217.37^†  ± 8.36	203.44^†  ± 8.42	182.16^†  ± 8.71
Hippocampal; tissue somatic index	0.04 ± 0.01	0.04^ns  ± 0.01	0.04^ns  ± 0.01	0.04^ns  ± 0.01	0.04^ns  ± 0.01

Value represents means ± S.D. for 6 rats per group. *P < 0.01 as compared to normal, nondiabetic rats group; ^†P < 0.01 as compared to nontreated diabetic rats.