Effects of the Kampo Formula Tokishakuyakusan on Headaches and Concomitant Depression in Middle-Aged Women

Table 1

Prevalence of each item in the physical and mental health domains in the Menopausal Health Related Quality of Life (MHR-QOL) questionnaire (%, 𝑁=345).

	0-1 time a month	1-2 times a week	3-4 times per week	Almost every day
Physical health domain
Nausea	78.5	13.4	2.3	5.8
Dizziness	65.4	22.2	5.2	7.3
Numbness	60.4	13.5	6.7	19.4
Muscle and joint pains	12.8	18.6	13.3	55.4
Tiredness	14.5	21.2	15.1	49.3
Headaches	47.2	27.5	11.6	13.6
Frequent urination	52.5	15.2	8.2	24.2
Hot flushes	45.3	18.0	15.1	21.5
Night sweats	55.4	17.4	10.4	16.8
Mental health domain
Loss of interest in things	51.9	18.1	13.1	16.9
Lack of enjoyment	48.7	22.0	11.9	17.4
Low energy	34.9	27.3	14.2	23.5
Depressed mood	30.8	27.6	15.7	25.9
Poor memory	27.5	32.5	20.6	19.4
Difficulty in concentration	31.6	29.3	20.3	18.8
Frightened/panicky feelings	46.2	22.7	15.4	15.7
Feel tense/wound up	37.5	24.1	17.2	21.2
Dissatisfaction with sexual relationship	85.0	6.8	2.9	5.3
Difficulty in initiating sleep	46.4	18.8	11.6	23.2
Nonrestorative sleep	34.5	21.4	13.6	30.4
Low self-esteem	39.1	21.0	12.0	28.0