The Inhibition of the Components from Shengmai Injection towards UDP-Glucuronosyltransferase

Figure 2

Determination of inhibition type and parameters () of OD towards UGT1A6-catalyzed 4-MU glucuronidation reaction. (a) Dose-dependent inhibition of OD towards UGT1A6-catalyzed 4-MU glucuronidation. (b) Dixon plot of inhibition of OD towards UGT1A6-catalyzed 4-MU glucuronidation. (c) Lineweaver-Burk plot of inhibition of OD towards UGT1A6-catalyzed 4-MU glucuronidation. (d) Second plot of inhibition of OD towards UGT1A6-catalyzed 4-MU glucuronidation. The data point represents the mean value of duplicate experiments.

(a)

(b)

(c)

(d)