The Inhibition of the Components from Shengmai Injection towards UDP-Glucuronosyltransferase

Figure 6

Determination of inhibition type and parameters () of RU towards UGT1A4-catalyzed TFP glucuronidation reaction. (a) Dose-dependent inhibition of RU towards UGT1A4-catalyzed TFP glucuronidation. (b) Dixon plot of inhibition of RU towards UGT1A4-catalyzed TFP glucuronidation. (c) Lineweaver-Burk plot of inhibition of RU towards UGT1A4-catalyzed TFP glucuronidation. (d) Second plot of RU’s inhibition towards UGT1A4-catalyzed TFP glucuronidation. The data point represents the mean value of duplicate experiments.

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