Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 2 / Review Article
Assessment of Registration Information on Methodological Design of Acupuncture RCTs: A Review of 453 Registration Records Retrieved from WHO International Clinical Trials Registry Platform Table 2 Overall assessment of methodological design based on registration records of acupuncture RCTs.
Overall ClinicalTrials.gov ISRCTN ChiCTR ANZCTR IRCT JPRN EU-CTR DRKS ReBec KCT NTR 453 (%) 213 (%) 78 (%) 66 (%) 52 (%) 16 (%) 5 (%) 4 (%) 3 (%) 3 (%) 11 (%) 2 (%) Not mentioned randomization methods 346 (76.4) 209 (98.1) 78 (100) 10 (15.2) 5 (9.6) 16 (100) 5 (100) 4 (100) 3 (100) 3 (100) 11 (100) 2 (100) Adequate randomization methods 107 (23.6) 4 (1.9) 0 (0) 56 (84.8) 47 (90.4) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) Randomized number table 22 1 0 16 5 0 0 0 0 0 0 0 Computer software or computerised sequence generation 81 2 0 40 39 0 0 0 0 0 0 0 Coin-tossing and dice-rolling 4 1 0 0 3 0 0 0 0 0 0 0 Not mentioned allocation concealment 403 (89.0) 207 (97.2) 78 (100) 65 (98.5) 9 (17.3) 16 (100) 5 (100) 4 (100) 3 (100) 3 (100) 11 (100) 2 (100) Adequate allocation concealment 48 (10.6) 6 (2.8) 0 (0) 1 (1.5) 41 (78.8)
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0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) Opaque sealed envelopes 29 3 0 0 26 0 0 0 0 0 0 0 Numbered containers 4 1 0 0 3 0 0 0 0 0 0 0 Central allocation 15 2 0 1 12 0 0 0 0 0 0 0 Not mentioned blinding 97 (21.4) 12 (5.6) 53 (67.9) 26 (39.4) 1 (1.9) 0 (0) 5 (100) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) Mentioned blinding 356 (78.6) 201 (94.4) 25 (32.1) 40 (60.6) 51 (98.1) 16 (100) 0 (0) 4 (100) 3 (100) 3 (100) 11 (100) 2 (100) Open 70 43 0 6 8 3 0 2 1 0 6 1 Single-blind 136 75 16 22 6 7 0 1 1 3 5 0 Double-blind 147 83 9 12 34 6 0 1 1 0 0 1 Not mentioned who was blinded 73 31 17 1 3 13 0 2 2 3 0 1 Adequate blinding 210 (46.4) 127 (59.6) 8 (10.3) 33 (50.0) 37 (71.2) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 5 (45.5) 0 (0)
Two records reported that allocation is not concealed (ACTRN12612000032853, ACTRN12609000698279).