Assessment of Registration Information on Methodological Design of Acupuncture RCTs: A Review of 453 Registration Records Retrieved from WHO International Clinical Trials Registry Platform
Table 3
The influence on the methodological design of RCTs registration by the authorization of Ethics Committee.
Without ethics approval (327) (%)
With ethics approval (126) (%)
Not mentioned randomization methods
308 (94.2)
38 (30.2)
Adequate randomization methods
19 (5.8)
88 (69.8)
206.698
0.000
Not mentioned allocation concealment
318 (97.2)
85 (67.5)
Adequate allocation concealment
9 (2.8)
39 (31.0)
*
77.865
0.000
Not mentioned blinding
72 (22.0)
25 (19.8)
Mentioned blinding
255 (78.0)
101 (80.2)
Open
52
18
Single-blind
103
33
Double-blind
100
50
Not mentioned who was blinded
53
20
Adequate blinding
150 (45.9)
63 (50.0)
0.471
0.491
Two records reported that allocation is not concealed (ACTRN12612000032853, ACTRN12609000698279).
