Research Article
Acupoint Application in Patients with Chronic Stable Angina Pectoris: Study Protocol of a Randomized, Double-Blind, Controlled Trial
| | Screening | Baseline (randomization) | Treatment | Follow up |
| Week | −4 | 0 | 4 | 8 | Informed consent | × | | | | In/exclusion criteria | | × | | | Vital signs | × | × | × | | Medical history | × | | | | Concomitant disease/medication | × | × | × | × | Diary card distributed/review | × | × | × | × | Total frequency of angina attack | | × | × | × | VAS scoring | | × | × | × | Consumption of nitroglycerin or Suxiao Jiuxin dropping pills | | × | × | × | CCS angina class | | × | × | × | SAQ scoring | | × | × | × | SAS and SDS scoring | | × | × | × | ECG | | × | × | × | Echocardiography | | × | | | Blood, urine, and stool tests | | × | | | Blood glucose and lipid tests | | × | | | Liver and renal function tests | | × | | | AEs | | × | × | × | Reasons to withdrawal | | | × | × | Safety evaluation | | × | × | | Compliance | | × | × | × |
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CCS = the Canadian Cardiovascular Society; SAQ = Seattle Angina Questionnaire; SAS = self-rating anxiety scale; SDS = self-rating depression scale; VAS = visual analogue scale; ECG = electrocardiograph; and AEs = adverse events.
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