Evaluation of Preclinical Assays to Investigate an Anthroposophic Pharmaceutical Process Applied to Mistletoe (Viscum album L.) Extracts

Table 1

Comparison of ED50 [μg/mL] values of Viscum album extract (VAE) Mali and anthroposophically processed Viscum album extract (APVAE) Mali in five different cell lines. Mean ± SD based on 8 independent experiments each. 4th column: APVAE ED50 values expressed relative to VAE data set to 100%. 5th column: 𝑡-test for independent samples.

Cell line	ED50 VAE Mali	ED50 APVAE Mali	ED50 APVAE Mali	𝑃 (𝑡-test)
	[mean ± SD]	[mean ± SD]	[%]
NCI-H460	70 ± 13 µg/mL	70 ± 14 µg/mL	99.0%	0.915
DU-145	48 ± 5 µg/mL	52 ± 6 µg/mL	106.7%	0.277
HCC1143	71 ± 26 µg/mL	76 ± 14 µg/mL	106.9%	0.647
MV3	56 ± 8 µg/mL	63 ± 8 µg/mL	111.3%	0.141
PA-TU-8902	355 ± 32 µg/mL	353 ± 42 µg/mL	99.5%	0.922