Neurotrophic Signaling Factors in Brain Ischemia/Reperfusion Rats: Differential Modulation Pattern between Single-Time and Multiple Electroacupuncture Stimulation
Multiple EA stimulation improved neurofunctional behaviors after ischemia/reperfusion. (a) Corner turn test performance. (b) Foot-fault test performance. Note that multiple EA treatment significantly reduced the left turn percentage in corner turn test at days 3 and 7 of reperfusion, whereas single-time EA stimulation had the tendency but no obvious effect in decreasing the left turn percentage (at day 1 of reperfusion). ISC: ischemia group. ISC + EA: ischemia plus EA group; Rep 1 d: day 1 of reperfusion; Rep 3 d: day 3 of reperfusion; Rep 7 d: day 7 of reperfusion. (a) , ISC versus ISC + EA; , ISC versus sham. (b) , . ISC versus sham. for sham group; for ISC group and ISC + EA group, respectively.