Hepatoprotective Effects of Silybum marianum (Silymarin) and Glycyrrhiza glabra (Glycyrrhizin) in Combination: A Possible Synergy
Figure 2
The histological structure of the rat liver. “U” is a normal control; V, W, and X are negative controls representing hepatic injuries at 2, 4, and 6 weeks, respectively; Y and Z are cases representing hepatic injury recovery after 6 weeks of combined SLN and GLN treatment. The arrows represent the status of the cells in different conditions: apoptotic bodies (yellow arrow), degenerated hepatocytes (red arrow), portal area infiltrated by mononuclear inflammatory cellular exudates mainly containing lymphocytes (gray arrow), steatosis (white arrow), binucleated cells (orange arrow), dilated hepatic sinusoids (green arrow), necrosis (black arrow), diffused Kupffer cells (blue arrow), and the central vein (brown arrow).
