Lingonberry (Vaccinium vitis-idaea L.) Exhibits Antidiabetic Activities in a Mouse Model of Diet-Induced Obesity
Table 2
Blood parameters at the end of the treatment.
CHOW
Control DIO
V.vitis-idaea
125 mg/kg
250 mg/kg
500 mg/kg
Triglycerides (mmol/L)
0.83 ± 0.08
0.74 ± 0.03
0.65 ± 0.04
0.67 ± 0.06
0.72 ± 0.04
Total cholesterol (mmol/L)
1.76 ± 0.15
3.34 ± 0.13*
3.09 ± 0.19*
2.96 ± 0.16*†
3.46 ± 0.15*
HDL (mmol/L)
0.69 ± 0.1
1.28 ± 0.04*
1.30 ± 0.07*
1.23 ± 0.07*
1.34 ± 0.03*
LDL (mmol/L)
0.69 ± 0.04
1.7 ± 0.1*
1.72 ± 0.09*
1.49 ± 0.11*†
1.77 ± 0.11*
Insulin (ng/mL)
4.48 ± 0.81
41.96 ± 18.88
43.71 ± 22.79
40.45 ± 15.45
29.11 ± 8.78
Leptin (ng/mL)
25.97 ± 1.52
34.09 ± 1.60*
34.20 ± 1.86*
35.65 ± 2.22*
36.94 ± 0.92*
Adiponectin (µg/mL)
17.29 ± 0.54
13.44 ± 0.96*
14.57 ± 0.82*
15.35 ± 1.60*
13.87 ± 1.13*
Leptin/adiponectin
1.50 ± 0.07
2.64 ± 0.20*
2.37 ± 0.12*
2.50 ± 0.25*
2.90 ± 0.32*
ALT (U/L )
26.18 ± 2.71
37.09 ± 3.47*
34.66 ± 4.47*
32.18 ± 4.90*
45.66 ± 6.50*
AST (U/L)
123.64 ± 23.50
109.45 ± 8.70*
98.50 ± 12.58*
102.54 ± 8.22*
116.16 ± 11.17
Creatinine (U/L)
51.40 ± 4.40
53.09 ± 5.11
59.83 ± 11.38†
55.81 ± 6.59
64.50 ± 11.35†
Alc. phosphatase (U/L)
35.45 ± 2.58
64.90 ± 20.00*
39.66 ± 3.06†
39.63 ± 3.63†
47.83 ± 3.82†
All values are mean ± SEM (). *indicates a value < 0.05 which is significantly different from CHOW group, and †indicates a value < 0.05 which is significantly different from DIO control group () as assessed by ANOVA test.
