Comparison of Electroacupuncture and Morphine-Mediated Analgesic Patterns in a Plantar Incision-Induced Pain Model

Figure 1

Effect of repeated daily EA treatments on PI-induced pain. (a) Summary of the protocols used in this experiment. BL: baseline on one day before PI; D: postplantar incision day; EA: electroacupuncture; h: hour; PI: plantar incision, marked by a solid triangle; pre: before daily EA treatment. (b) Mechanical allodynia, (c) heat hyperalgesia. Naïve: group without PI surgery or EA treatment, EA: group with repeated EA treatments, EA+PI: group for PI with repeated EA treatments, and Sham+PI: group for PI with repeated sham needle insertions; # < 0.05, ## < 0.01, ### < 0.001 groups versus Naïve; ∗ < 0.05, ∗∗ < 0.01, ∗∗∗ < 0.001 EA+PI versus Sham+PI; one-way ANOVA with Tukey’s multiple comparison test; (Naïve), 4 (EA), 7 (Sham+PI), and 9 (EA+PI).

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