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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 682014, 9 pages
Research Article

Proof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer’s Dementia

1Lawson Health Research Institute, Lab FB125, 268 Grosvenor Street, London, ON, Canada N6A 4V2
2Department of Psychiatry, University of Western Ontario, London, ON, Canada N6A 3K7
3Medical and Scientific of HG & H Pharmaceuticals (Pty) Ltd., 193 Bryanston Drive, Bryanston 2192, South Africa
4Department of Psychiatry, School of Medicine, University of Puerto Rico, San Juan, PR 00936-5067, USA
5Medical and Scientific Affairs, P L Thomas & Co., Inc., Morristown, NJ 07960, USA
6Department of Psychiatry, Island Medical Program, University of Victoria, University British Columbia Extended Medical Campus, Victoria, BC, Canada V8W 2Y2
7Department of Psychiatry, Northern Ontario School of Medicine, Thunder Bay, ON, Canada P7B 5E1

Received 21 May 2014; Revised 16 August 2014; Accepted 2 September 2014; Published 19 October 2014

Academic Editor: Kuzhuvelil B. Harikumar

Copyright © 2014 Simon Chiu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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