Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 2

Research Article

Proof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer’s Dementia

Table 2

Zembrin extract effect on HAM-D in healthy control subjects.

Average HAM-DSD value
1-tailed
Effect size:
% change

Before Zembrin () 1.671.926.9%
decrease on HAM-D
After Zembrin ()1.221.9

Before placebo () 1.952.113.8%
decrease on HAM-D
After placebo ()1.681.5

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