Evidence-Based Complementary and Alternative Medicine

Review Article

Genus Caulophyllum: An Overview of Chemistry and Bioactivity

Table 1

Chemical structures of alkaloids (1–22) from genus Caulophyllum.


No.	Compounds	Formula	Sources^a	References

1	Magnoflorine		Cr, Ct	[85, 86]
2	Taspine	C₂₀H₁₉NO₆	Cr, Ct	[25, 86]
3	Boldine	C₁₉H₂₁NO₄	Cr	[86]
4	Anagyrine	C₁₅H₂₀N₂O	Cr, Ct	[20, 85, 86]
5	Sparteine	C₁₅H₂₆N₂	Cr, Ct	[25]
6	N-methylcytisine	C₁₂H₁₆N₂O	Cr, Ct	[20, 85–87]
7	Cytisine	C₁₁H₁₄N₂O	Cr	[86]
8	5,6-Dehydro--isolupanine	C₁₅H₂₂N₂O	Cr, Ct	[25, 86]
9	Lupanine	C₁₅H₂₄N₂O	Cr, Ct	[25, 86]
10	Baptifoline or Argentamin	C₁₅H₂₀N₂O₂	Ct	[85, 86]
11	O-acetylbaptifolin		Ct	[20]
12	-isolupanine	C₁₅H₂₄N₂O	Cr, Ct	[25, 86]
13	Thalictroidine	C₁₄H₁₉NO₂	Ct	[20, 25]
14	Caulophyllumine A	C₁₅H₂₁NO₄	Ct	[20]
15	Caulophyllumine B	C₁₄H₁₉NO	Ct	[20]
16	Piperidylacetophenone	C₁₅H₂₁NO₃	Ct	[20]
17	Caulophine		Cr	[88]
18	Caulophylline A	C₂₀H₂₃NO₅	Cr	[13]
19	Caulophylline B	C₁₉H₂₁NO₅	Cr	[13]
20	Caulophylline C	C₂₀H₂₄NO₅	Cr	[13]
21	Caulophylline D	C₂₀H₂₄NO₆	Cr	[13]
22	Caulophylline E	C₁₈H₁₇NO₄	Cr	[13]

Cr means C. robustum; Ct means C. thalictroides.