Validation of the Antidiabetic and Hypolipidemic
Effects of Clitocybe nuda by Assessment of Glucose
Transporter 4 and Gluconeogenesis and AMPK
Phosphorylation in Streptozotocin-Induced Mice
Figure 5
The phospho-AMPK (Thr172) protein contents in (a) liver and (b) skeletal muscle and (c) GLUT4 protein contents inskeletal muscle of the mice by oral gavage extract of Clitocybe nuda. Protein was separated by 12% SDS-PAGE detected by western blot. All values are means S.E. (). #P < 0.05, ##P < 0.01, and ###P < 0.001 compared with the control (CON) group; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the streptozotocin + vehicle (distilled water) (STZ) group. C1, C2, and C3: extracts of Clitocybe nuda (C1: 0.2, C2: 0.5, and C3: 1.0 g/kg bodyweight); Metf: metformin (0.3 g/kg body weight).