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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 715937, 8 pages
Research Article

Gene Expression Profile of Increased Heart Rate in Shensongyangxin-Treated Bradycardia Rabbits

1State Key Laboratory of Translational Cardiovascular Medicine, Fuwai Hospital & Cardiovascular Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Bei-Li-Shi Road, Xi-Cheng District, Beijing 100037, China
2Integration of Traditional and Western Medical Research Academy of Hebei Province, Shijiazhuang 050035, China

Received 21 August 2014; Revised 22 October 2014; Accepted 3 November 2014; Published 27 November 2014

Academic Editor: Adair Santos

Copyright © 2014 Zhouying Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplement Tables showed all altered genes after SSYX treatment (Table 1) and showed 846 restored genes between SSYX-Down versus lesion-Up and SSYX-Up versus lesion-Down (Table 2). Supplement Figure 1 showed Gene ontology classification of differentially expressed genes after SSYX treatment. Representation of biological process items obtained from the deregulated genes after SSYX treatment, (A) downregulated and (B) upregulated (according to a unilateral Fisher exact test and P < 10-4). Supplement Figure 2 displayed the results from quantitative real-time RT-PCR. (A) Comparison of results obtained with the expression chip and quantitative real-time RT-PCR for mRNA levels of selected genes in sham vs. model group and (B) in SSYX vs. model group.

  1. Supplementary Material