Table 2: Changes of volume, mean, and geometric mean diameter of the largest myoma per patient during the treatment. Median and interquartile range (IQR) are shown for the volume parameters for which normal distribution was rejected, and mean ± SD is shown for the diameter parameters for which normal distribution was not rejected. values for intergroup comparison by Mann-Whitney U test.

GroupiCRTibolone

3428
Volume (mm³)
 Visit 11787 (559; 6107)1063 (520; 8060)0.35
 Visit 31086 (0; 5991)1096 (448; 4695)0.91
Volume change (%)−30.3 (−100.0; +12.7)+4.7 (−35.9; +88.3)0.016
Mean diameter (mm)
 Visit 118.7 ± 10.616.5 ± 10.70.37
 Visit 315.1 ± 12.814.8 ± 8.50.85
Mean diameter change (%)−25.6 ± 47.6+6.6 ± 54.70.021
Geometric mean diameter (mm)
 Visit 118.6 ± 10.516.0 ± 9.20.35
 Visit 314.8 ± 12.914.4 ± 8.90.91
Geometric mean diameter Change (%)−26.6 ± 48.8+6.1 ± 58.00.016