Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients

Figure 5

Odds ratios with 95% confidence intervals for the effect of mistletoe dosage on relative frequencies of (a) all ADRs, (b) pyrexia and injection site ADRs only, and (c) other ADRs (diarrhoea, nausea, vomiting, chills, fatigue, malaise, headache, increased blood glucose, decreased blood pressure, pruritus, rash, urticaria, and syncope). The relative frequencies of ADRs in response to low, moderate and high doses of mistletoe were compared to the relative frequency of ADRs that occurred in response to very low dose mistletoe. ns = not significantly different (𝑃>0.05/3), significance levels: ^∗∗𝑃<0.01/3, ^∗∗∗𝑃<0.001/3. Note that normally accepted significance levels are divided by three in accordance with the Bonferroni correction for multiple comparisons.

(a)

(b)

(c)