Cytotoxic Activities against Breast Cancer Cells of Local Justicia gendarussa Crude Extracts

Table 4

Percentage viability of MDA-MB-231 and MDA-MB-468 cells in kaempferol, naringenin, and a mixture of kaempferol and naringenin.

Cells	Concentration (μg/mL)	3.91	7.81	15.63	31.25	62.5	125	250	500
MDA-MB-231	Kaempferol	82.16 ± 0.06	81.07 ± 0.06	61.48 ± 1.59	50.96 ± 0.09	36.45 ± 0.04	27.45 ± 0.06	43.52 ± 0.02	77.37 ± 3.30
	Naringenin	85.53 ± 0.06	100.23 ± 0.06	87.13 ± 0.07	69.35 ± 0.02	93.79 ± 0.07	83.97 ± 0.04	47.91 ± 0.04	13.48 ± 0.01
	Mixture of kaempferol and naringenin	72.42 ± 0.11	66.94 ± 0.11	62.17 ± 0.64	56.10 ± 0.12	27.15 ± 0.34	26.37 ± 0.03	23.42 ± 0.11	23.32 ± 0.22
MDA-MB-468	Kaempferol	96.00 ± 0.07	74.82 ± 0.02	53.99 ± 0.03	31.64 ± 0.03	17.67 ± 0.02	12.73 ± 0.01	7.05 ± 0.01	11.33 ± 0.03
	Naringenin	85.62 ± 2.03	94.26 ± 2.30	117.71 ± 0.07	112.18 ± 3.26	58.08 ± 1.51	13.54 ± 0.02	3.24 ± 0.01	3.94 ± 0.01
	Mixture of kaempferol and naringenin	92.02 ± 0.11	89.79 ± 0.01	83.99 ± 0.98	70.82 ± 0.04	29.38 ± 0.04	16.44 ± 0.02	13.34 ± 0.03	13.33 ± 0.06

Values are mean ± STDEV for 3 replicates < 0.05, < 0.01, and < 0.001 compared to control (untreated cell).