Table 3: Organ weight values of control group and rats treated with C. papaya leaf extract measured during the subchronic toxicity study. The relative organ weight per 100 g body weight recorded at the end of the study.

OrganControl0.01 g/kg BW0.14 g/kg BW2 g/kg BW

Male rats
 Lung0.31 ± 0.030.36 ± 0.090.37 ± 0.070.35 ± 0.08
 Heart0.27 ± 0.020.29 ± 0.050.27 ± 0.020.27 ± 0.03
 Liver2.87 ± 0.143.05 ± 0.662.80 ± 0.372.82 ± 0.27
 Stomach0.38 ± 0.030.38 ± 0.050.39 ± 0.060.37 ± 0.05
 Spleen0.13 ± 0.020.15 ± 0.010.15 ± 0.010.15 ± 0.03
 GIT0.34 ± 0.130.36 ± 0.080.28 ± 0.080.32 ± 0.09
 Kidney (left)0.31 ± 0.030.30 ± 0.060.29 ± 0.020.29 ± 0.03
 Kidney (right)0.32 ± 0.030.29 ± 0.050.29 ± 0.020.29 ± 0.03
 Testis (left)0.35 ± 0.030.34 ± 0.040.34 ± 0.030.35 ± 0.03
 Testis (right)0.35 ± 0.030.34 ± 0.040.35 ± 0.040.34 ± 0.02
 Adrenal (left)0.01 ± 0.000.01 ± 0.000.01 ± 0.000.01 ± 0.00
 Adrenal (right)0.01 ± 0.000.01 ± 0.000.01 ± 0.000.00 ± 0.00
Female rats
 Lung0.46 ± 0.060.45 ± 0.090.44 ± 0.070.45 ± 0.09
 Heart0.32 ± 0.030.31 ± 0.020.31 ± 0.020.31 ± 0.03
 Liver2.95 ± 0.303.02 ± 0.272.85 ± 0.193.02 ± 0.26
 Stomach0.50 ± 0.070.46 ± 0.070.51 ± 0.080.49 ± 0.08
 Spleen0.17 ± 0.020.17 ± 0.020.18 ± 0.020.18 ± 0.02
 GIT0.45 ± 0.120.45 ± 0.180.43 ± 0.060.39 ± 0.04
 Kidney (left)0.30 ± 0.030.29 ± 0.040.29 ± 0.030.31 ± 0.03
 Kidney (right)0.31 ± 0.030.31 ± 0.030.30 ± 0.020.31 ± 0.02
 Ovary (left)0.02 ± 0.010.02 ± 0.000.02 ± 0.010.04 ± 0.06
 Ovary (right)0.02 ± 0.000.02 ± 0.000.02 ± 0.010.02 ± 0.01
 Adrenal (left)0.01 ± 0.000.02 ± 0.000.01 ± 0.010.01 ± 0.00
 Adrenal (right)0.01 ± 0.010.01 ± 0.000.01 ± 0.000.01 ± 0.01

Values are expressed as mean ± standard deviation (/group).