Research Article
Red Sea Suberea mollis Sponge Extract Protects against CCl4-Induced Acute Liver Injury in Rats via an Antioxidant Mechanism
Table 2
Effect of Suberea mollis sponge extract (SMSE) and silymarin on liver GPx, SOD, and CAT measured in CCl4-induced hepatotoxicity in rats.
| Treatment regimen | GPx (mU/g tissue) | SOD (U/g tissue) | CAT (U/g tissue) |
| Control | 24.8 ± 6.9 | 18.3 ± 4.8 | 8.2 ± 0.2 | CCl4 | 5.3 ± 9.2a | 11.13 ± 3.6a | 4.8 ± 1.3a | CCl4 + silymarin (100 mg/kg) | 15.5 ± 4.7b | 17.8 ± 2.3b | 8.3 ± 0.3b | CCl4 + SMSE (100 mg/kg) | 29.1 ± 10.1b | 12.7 ± 2.8 | 4.5 ± 1.3 | CCl4 + SMSE (200 mg/kg) | 32.5 ± 13.6b | 16.8 ± 3.6 | 7.65 ± 0.5b | CCl4 + SMSE (400 mg/kg) | 42.3 ± 9.9b | 32.7 ± 6.5b | 7.9 ± 0.7b |
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Data are mean ± SD of five animals.
aSignificantly different from control group .
bSignificantly different from the CCl4 group .
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