Apocynum Tablet Protects against Cardiac Hypertrophy via Inhibiting AKT and ERK1/2 Phosphorylation after Pressure Overload

Figure 6

AT inhibited the phosphorylation of ERK1/2 and AKT in response to TAC. (a) Phosphorylated (p)-Thr202/204 extracellular signal-regulated kinase (ERK) 1/2 and (b) p-Ser473 protein kinase B (AKT), and quantified data for (c) p-ERK1/2 and for (d) p-AKT. Data (mean ± SEM, 𝑛=3) were expressed as fold changes from total protein (ERK1/2, AKT) and control (NS-SHAM). ^∗𝑃<0.05 study group versus NS-SHAM group.

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