White Pepper and Piperine Have Different Effects on Pharmacokinetics of Puerarin in Rats

<table>Change of the <svg height="15.65" id="M71" style="vertical-align:-3.25793pt" version="1.1" viewbox="0 0 59.662498 15.65" width="59.662498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> values of puerarin as compared with control, when simultaneously administered with piperine (10 and 20 mg/kg) or pepper (125 and 250 mg/kg) and puerarin. Asterisks signs designate significant differences: <svg height="17.825001" id="M74" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 69.150002 17.825001" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control group given puerarin only; <svg height="17.825001" id="M75" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 76.137497 17.825001" width="76.137497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control group given puerarin only.</table>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: White Pepper and Piperine Have Different Effects on Pharmacokinetics of Puerarin in Rats 