Multifunctional Effects of Mangosteen Pericarp on Cognition in C57BL/6J and Triple Transgenic Alzheimer’s Mice

Figure 1

MP induced neuroprotection through increasing BDNF in adult mouse hippocampal slices. (a) The cell death level of hippocampal slices was characterized with PI staining after treatment with MP (10 μM) or DMSO. The scale bar of PI staining is 500 μm. (b) The quantification of PI staining. Treatment with MP significantly decreased the cell death level. (c) The results of BDNF ELISA in the hippocampal slices. Treatment with MP increased the level of BDNF in the hippocampal slices. Data are expressed as means ± SEM, = 9–12 slices/group. , compared with the DMSO group.

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