Multifunctional Effects of Mangosteen Pericarp on Cognition in C57BL/6J and Triple Transgenic Alzheimer’s Mice

Figure 5

Neuroprotective effects of the MP diet in 3×Tg-AD mice. Immunostaining images of neurons in the hippocampus (a), calbindin levels in the hippocampus (b), BDNF in the hippocampus (c), ChAT in the MS/DB region (d), TH in the LC region (e), and 5-HT in the raphe nucleus (f). Scale bars are 100 μm in panel (a), 50 μm in panels (b) and (c), and 500 μm in panels (d)~(f). Arrowheads indicate positive staining signals. = 3–5/group.

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