Multifunctional Effects of Mangosteen Pericarp on Cognition in C57BL/6J and Triple Transgenic Alzheimer’s Mice

Table 3

The results of immunostaining in 3×Tg-AD mice after dietary supplementation.

Target	Regular diet	MP diet
NeuN	716 ± 28.69	1037 ± 78.30
Calbindin	20 ± 3.71	91 ± 9.91
BDNF	19 ± 1.01	27 ± 0.67
ChAT	42 ± 5.00	62 ± 5.80
TH	57 ± 4.66	111 ± 5.64
5-HT	36 ± 2.83	67 ± 5.41
APP	165 ± 4.07	159 ± 6.62
A	613 ± 29.39	656 ± 20.08
A	685 ± 14.72	604 ± 23.01^#
Tau pSer202	37 ± 2.22	19 ± 2.44^###

Each value represents the mean ± SEM ( = 3–5 for each group).
All values were compared with the regular diet group.
^*Increased (); ^**increased (); ^***increased ().
^#Decreased (); ^##decreased (); ^###decreased ().