Protective Effects of Berberine on Isoproterenol-Induced Acute Myocardial Ischemia in Rats through Regulating HMGB1-TLR4 Axis

Figure 5

Effect of berberine on HMGB1-TLR4 axis signaling C (control); M (model); P (propranolol (30 mg/kg)); D (berberine (30 mg/kg)); E (berberine (60 mg/kg)). Values are expressed as means ± SDs. Compared with control, ^#, ^##; compared with model, ^∗, ^∗∗.