Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 1

Research Article

Treatment of Rheumatoid Arthritis with Marine and Botanical Oils: An 18-Month, Randomized, and Double-Blind Trial

Table 1

Baseline characteristics in the three randomized groups.

Mean (SD) or median [IQR] ( = total) or percent ( = num) ( = total)Borage group ( )Combination group ( )Fish group ( ) value

Body mass index (kg/m2)29.4 (7.1)
( )
30.4 (8.2)
( )
31.4 (9.5)
( )
0.499
Female76.9 ( )80.0 ( )86.8 ( )0.415
Age 60.3 (9.2)60.5 (13.0)57.3 (12.3)0.295
Black/African-American 7.8 ( )
( )
2.2 ( )
( )
7.8 ( )
( )
0.428**
Does subject exercise? (yes)57.7 ( )51.1 ( )50.9 ( )0.738
Rheumatoid factor positive 73.9 ( )
( )
83.9 ( )
( )
72.7 ( )
( )
0.491
Log ESR value2.9 (1.1)
( )
2.7 (1.0)
( )
3.05 (1.0)
( )
0.199
CRP value0.6 0.3–1.5
( )
0.6 0.4–2.7
( )
0.8 0.4–1.7
( )
0.415*
Disability index (mHAQ) 0.5 0.1–0.7
( )
0.5  0.1–0.9
( )
0.5  0.1–0.9
( )
0.788*
Clinical Disease Activity Index34.4 (11.5)36.0 (12.6)35.8 (11.3)0.763
Simplified Disease Activity Index33.1 (27.0–47.1)
( )
34.1 (28.8–50.2)
( )
35.5 (30.8–46.2)
( )
0.442
Disease activity score 5.0 4.1–5.8
( )
4.8 3.9–5.7
( )
5.2 4.4–6.0
( )
0.404*
DAS remission (<2.6) 3.8 ( )
( )
4.6 ( )
( )
2.0 ( )
( )
0.859**
Total number of tender joints12.5 
7.5–18.0
11.0 
7.0–18.0
12.0 
8.0–20.0
0.936*
Total number of swollen joints12.0 
8.0–15.0
12.0 
8.0–19.0
12.0 
8.0–18.0
0.733*
Physician global 3.8 
3.0–5.8
4.0 
3.0–6.3
4.1 
3.0–7.0
0.646*
Patient global 5.0 
3.0–6.7
5.5 
4.0–7.0
5.0 
2.8–6.5
0.435*
Patients taking methotrexate 61.5
( )
68.9
( )
64.1
( )
0.748
Patients taking NSAIDS 28.8 ( )31.1 ( )26.4 ( )0.876
Patients taking corticosteroid 21.1
( )
24.4
( )
28.3
( )
0.696
Patients taking DMARDS 71.1
( )
77.8
( )
69.8
( )
0.647
Patients taking TNF blockers 50.0
( )
44.4
( )
50.9
( )
0.791
Morning stiffness (minutes)60.0 30.0–180.0
( )
60.0 35.0–120.0
( )
60.0 42.5–120.0
( )
0.439*
Duration of rheumatoid arthritis (years)7.4 3.0–15.3
( )
12.2 4.4–18.0
( )
6.3 4.2–18.9
( )
0.349*

value is from a Kruskal-Wallis test, median with the 25th and the 75th percentile is shown.
value is from a Fisher’s exact test. All other values come from a -test or chi-square.

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