Electroacupuncture Promotes Proliferation of Amplifying Neural Progenitors and Preserves Quiescent Neural Progenitors from Apoptosis to Alleviate Depressive-Like and Anxiety-Like Behaviours
Animal groups and schematic representations of the behaviour testing procedure. The rats were randomly divided into three groups ( per group): Normal (a naïve unchallenged group without any stress and any treatment), Model (rats which were exposed to 4-week CUS), and EA (model rats which received EA treatment in the last two weeks of the CUS procedure). For the latter 2 groups, 4-week CUS with/without 2-week EA treatment was performed. The forced swimming test (FST) was performed at the end of every week. The elevated plus-maze (EPM) test and the open field test (OFT) were performed before the CUS, at the end of week 2, week 3, and week 4. For analysis of cell proliferation, another batch of the rats, which was also divided into three groups and subjected to the same procedure, received a single injection of BrdU (200 mg kg1 i.p.) on the first day of the week 5 and was sacrificed (S) 24 h after BrdU administration.
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