Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation
((a), (b)). Lactobacillus numbers in the cecal contents and feces of loperamide-induced constipated rats after oral treatment of the test agents. Significant increases in viable Lactobacillus numbers were detected in cecal contents and feces 6 days after continuous oral treatment of 10 mg/kg FRe, liquid yoghurt single formula, or the three concentrations of BFRe, as compared with the loperamide control. In addition, greater increases in Lactobacillus numbers were detected with all three BFRe concentrations compared with equivalent doses of liquid yoghurt or FRe single formula. Values are expressed as means SD of five independent culture plates. The test agents, diluted 10-fold, were incubated at 37°C for 96 h under anaerobic conditions using candle jars, and all were administered in a 10 mL/kg volume. All solutions were administered as 10 mL/kg doses. and compared with the vehicle control by the LSD test. and compared with the loperamide control by the LSD test. 1 and compared with the vehicle control by the MW test. and compared with the loperamide control by the MW test.
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