Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation

Table 1

Body weight gain in loperamide-induced constipated rats during oral treatment of the test agents.

Groups	Body weights at			Body weight gains; (B − A)
	Initiation of treatment (A)*	5th treatment day	Last 6th treatment day (B)*
Controls
Vehicle	208.80 ± 4.97	263.00 ± 9.06	234.80 ± 9.12	26.00 ± 4.53
Loperamide	207.40 ± 3.97	258.20 ± 4.09	232.20 ± 5.76	24.80 ± 3.42
Single formula
FRe 5 mg/kg	209.60 ± 6.31	257.60 ± 7.50	233.20 ± 8.44	23.60 ± 3.65
FRe 10 mg/kg	209.00 ± 5.48	260.00 ± 12.06	233.60 ± 9.81	24.60 ± 4.67
Yoghurt	208.80 ± 8.23	259.40 ± 11.87	234.60 ± 11.72	25.80 ± 3.90
Mixed formula
BFRe 0.05%	209.00 ± 7.52	256.00 ± 8.51	232.00 ± 9.14	23.00 ± 2.55
BFRe 0.1%	211.40 ± 4.88	262.40 ± 7.23	236.20 ± 5.81	24.80 ± 1.10
BFRe 1%	209.60 ± 3.65	258.80 ± 0.84	235.40 ± 2.79	25.80 ± 1.48

Values are expressed as means ± SD of five rats, g.
Yoghurt: Bulgaris, a brand of commercial yoghurt (Namyang, Korea).
FRe: fermented rice extracts.
BFRe: mixed formula consisting of yoghurt and the appropriate percentages (0.05, 0.1, and 1%) of FRe.
All solutions were administered as 10 mL/kg doses.
*Fasted overnight.