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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 891310, 7 pages
http://dx.doi.org/10.1155/2014/891310
Research Article

Clinical Usefulness of Oral Supplementation with Alpha-Lipoic Acid, Curcumin Phytosome, and B-Group Vitamins in Patients with Carpal Tunnel Syndrome Undergoing Surgical Treatment

Hand Surgery Unit, Plastic Surgery Department, MultiMedica Holding S.p.A, Via Milanese, Sesto San Giovanni, 300-20099 Milan, Italy

Received 12 June 2013; Revised 2 December 2013; Accepted 3 December 2013; Published 19 January 2014

Academic Editor: Youn Chul Kim

Copyright © 2014 Giorgio Pajardi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We investigated the clinical usefulness of oral supplementation with a combination product containing alpha-lipoic acid, curcumin phytosome, and B-group vitamins in 180 patients with carpal tunnel syndrome (CTS), scheduled to undergo surgical decompression of the median nerve. Patients in Group A ( ) served as controls and did not receive any treatment either before or after surgery. Patients in Group B ( ) received oral supplementation twice a day for 3 months both before and after surgery (totaling 6 months of supplementation). Patients in Group C ( ) received oral supplementation twice a day for 3 months before surgery only. Patients in Group B showed significantly lower nocturnal symptoms scores compared with Group A subjects at both 40 days and 3 months after surgery (both values ). Moreover, patients in Group B had a significantly lower number of positive Phalen’s tests at 3 months compared with the other study groups ( ). We conclude that oral supplementation with alpha-lipoic acid, curcumin phytosome, and B-group vitamins twice a day both before and after surgery is safe and effective in CTS patients scheduled to undergo surgical decompression of the median nerve.