Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of β-Arrestin 2-Mediated Pathways in Hippocampus

Figure 1

Effects of XYS on body weight and behavior of rats treated with social isolation and CUMS. Body weight was measured once a week (a). A battery of behavioral tests was initiated 21 d after modeling, and the following parameters were measured: crossing trajectories (b), crossing numbers (c), rearing numbers (d), sucrose preference (e), and food consumption (f). Data are expressed as mean ± SD, 𝑛=10 per group. ^△𝑃<0.05, ^▲𝑃<0.01 versus control, ^∗𝑃<0.05, ^#𝑃<0.01 versus model.