Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of β-Arrestin 2-Mediated Pathways in Hippocampus

Figure 2

Effects of XYS on serum and cerebrospinal fluid hormone levels in depressive rats. Effect of XYS on serum ACTH (a), serum CORT (b), serum CRH (c), CSF CRH (d), serum urocortin 2 (e), and CSF urocortin (f). Data are expressed as mean ± SD, 𝑛=6 per group. ACTH: adrenocorticotropic hormone; CORT: corticosterone; CRH: corticotropin-releasing hormone; CSF: cerebrospinal fluid. ^△𝑃<0.05, ^▲𝑃<0.01 versus control, ^∗𝑃<0.05, ^#𝑃<0.01 versus model.

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