<i>Ananas comosus</i> L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression

<table>Effect of PLP and CA on CPT-1A expression in HepG2 cells based on the immunofluorescence assay using confocal microscopy. DMSO: DMSO-treated control cells; PLP-10, PLP-50: pineapple leaf phenol-treated (final concentrations of 10 and 50 <i>μ</i>g/mL, resp.) cells; CA-1 and CA-10: coumaric acid-treated (final concentrations of 1 and 10 <i>μ</i>g/mL, resp.) cells; and FB-1.4: fenofibrate-treated (final concentration of 1.4 <i>μ</i>g/mL) cells. 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vert-adv-y="480"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,30.39,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z" id="g113-47"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="228" vert-adv-y="228"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,33.48,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z" id="g113-49"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,39.983,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z" id="g113-50"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g></svg> versus DMSO controls.</table>

Evidence-Based Complementary and Alternative Medicine

fig7

Figure 7

Figure 7: <i>Ananas comosus</i> L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression 

Evidence-Based Complementary and Alternative Medicine

Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression

Figure 7