Recent Advances in Developing Insect Natural Products as Potential Modern Day Medicines
Figure 3
Effects of cantharidin on cell viability and morphological changes of human colorectal cancer cells. (a) Cells treated with 0, 5, 10, 20, or 40 μM cantharidin for 0, 24, 48, and 72 h and then harvested for determination of cell viability. (b) Cells exposed to 20 μM cantharidin for 24 h and then examined for morphological changes under phase-contrast microscopy. Data represent the mean ± SD of three experiments. From Huang et al., “Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways,” International Journal of Oncology, volume 38, pp. 1067-1073, 2011. Reprinted with permission of Spandidos Publications 2013.
