Research Article

Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra

Table 3

Effect of EESG and PEESG on secretions of NO, IL-6, and TNF-a in LPS-induced RAW264.7 cells.

GroupsDose (g/mL)NO (ng/mL)IL-6 (pg/mL)TNF-a (pg/mL)

Control0.229 ± 0.0839.497 ± 3.40237.995 ± 16.422

LPS0.19.308 ± 115.100 ± 3759.263 ±

LPS + DXM0.253.124 ± 23.531 ± 318.154 ±

PEESG405.298 ± 37.900 ± 617.741 ±
87.529 ± 65.971 ± 1730.369 ±
1.68.106 ± 84.457 ± 16.6592682.134 ±

Cells were treated with LPS (0.1 g/mL) for 24 h in the absence or presence of samples (1.6, 8.0, and 40 g/mL). The data were presented as mean ± SD (). Dexamethasone (DXM) was employed as a positive control. # and ## mean P < 0.01 and P < 0.001 correspondingly compared with control group while , , and mean P < 0.05, P <0.01, and P < 0.001 correspondingly compared with LPS group.