Protective Effect of Solanum nigrum Leaves Extract on Immobilization Stress Induced Changes in Rat’s Brain

Table 1

Groups	SOD (U/mg protein)	GST (U/mg protein)	CAT (U/mg protein)	MDA (nmol/mg protein)	GSH (mmol/mg protein)
Control (5)	10.122±2.21	95.541±5.21	10.216±2.21	11.485±1.11	8.584±1.21
Stressed (5)	3.124±1.31^d	30.548±5.21^c	2.652±2.12^d	22.016±2.15^d	2.214±3.10^d
Crude extract (5)	11.214±1.15	90.486±7.18	11.014±1.11	12.521±1.94	7.254±3.25
Alkaloid fraction (5)	9.354±2.05	85.214±11.211	8.524±2.36	10.598±1.15	7.965±2.15
Pre-stressed-alkaloid treatment (5)	7.254±1.45^c′	50.247±7.51^b′	4.541±2.11^a′	15.121±2.12^a′	4.254±0.85^a′
Post-stressed-alkaloid treatment (5)	7.248±1.89^a′	71.294±15.14^b′	8.547±2.15^b′	18.154±3.12^c′	7.214±1.36^b′
Flavonoid (5)	12.254±3.11	104.965±17.21	11.278±2.98	12.852±2.98	9.524±2.25
Pre-stressed-flavonoid treatment (5)	7.214±2.02^a′	80.521±11.45^a′	8.154±2.16^b′	9.541±2.75^a′	8.325±2.65^a′
Post-stressed-flavonoid treatment (5)	11.264±1.11^a′	89.547±11.14^b′	12.524±3.72^c′	7.521±3.45^c′	12.521±2.65^d′

The number of experimental rats is indicated in the parenthesis. ^a𝑃<0.05, ^b𝑃<0.02, ^c𝑃<0.01, ^d𝑃<0.001, as compared with control rats. ^a′𝑃<0.05, ^b′𝑃<0.02, ^c′𝑃<0.01, ^d′𝑃<0.001, as compared with stress alone.