Research Article
In Silico Investigation of Potential PARP-1 Inhibitors from Traditional Chinese Medicine
Table 1
Scoring functions of top candidates and A927929 from TCM database screening.
| | Name | Resource | LigScore2 Dreiding |
-PLP1 | -PLP2 | -PMF | Dock score |
| | Isopraeroside IV | Angelica dahurica | 6.42 | 122.67 | 116.48 | 163.17 | 100.596 | | Picrasidine M | Picrasma quassioides (D. Don) Benn. | 6.92 | 125.68 | 121.49 | 162.36 | 92.256 | | Aurantiamide acetate | Artemisia annua L. | 6.74 | 136.86 | 132.63 | 159.08 | 88.910 | | A927929
*
| | 6.10 | 118.83 | 115.73 | 120.22 | 52.093 |
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Control.
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