Amoebicidal Activity of Essential Oil of Dysphania ambrosioides (L.) Mosyakin & Clemants in an Amoebic Liver Abscess Hamster Model
Amoebas marked with 220 kDa lectin during ALA 7 days after inoculation. (a) Normal histology of hamster liver (control). (b) Amoebic liver abscess after 7-day inoculation. Hamsters showed fragmented amoeba (arrow), fibrosis, and inflammatory infiltrate at the lesion. (c) Hamsters treated with 8 mg/kg of Ascaridole showed less fibrosis and small granulomas (arrow), whereas (d) hamsters treated with high Ascaridole dose had lesion by Entamoeba histolytica (arrow) reduced, without inflammatory infiltrate, reverted completely.