Electroacupuncture Improves Trinitrobenzene Sulfonic Acid-Induced Colitis, Evaluated by Transcriptomic Study

Table 1

Expression levels of cytokine genes in colonic tissues treated with TNBS and/or EA (100 Hz) at PC3 and PC6 acupoints.

Gene	Fold changes
	TNBS^a	EA^b
Interleukin-1𝛼	1.18±0.64	−1.50±0.30
Interleukin-1𝛽	1.34±0.54	−1.84±0.10
Interleukin-3	1.07±0.09	−1.04±0.05
Interleukin-4	1.02±0.04	1.01±0.05
Interleukin-6	1.54±0.88	−1.66±0.34
Interleukin-7	1.10±0.06	−1.17±0.04
Interleukin-9	1.02±0.13	−1.16±0.07
Interleukin-10	−1.15±0.17	1.00±0.09
Interleukin-11	2.87±2.64	−1.84±0.54
Interleukin-13	5.72±6.34	−3.59±0.30
Interleukin-15	−2.28±0.23	−1.16±0.40
Interleukin-16	1.04±0.01	−1.09±0.04
Interleukin-17B	1.03±0.05	−1.12±0.06
Interleukin-18	3.11±3.44	−4.34±0.23
Interleukin-20	1.05±0.02	−1.08±0.01
Interleukin-24	1.02±0.05	−1.06±0.06
Interleukin-25	1.14±0.54	−1.49±0.25
Interferon-𝛽	1.07±0.14	−1.03±0.09
Interferon-𝛾	1.20±0.13	−1.70±0.09
Tumor necrosis factor-𝛼	1.08±0.07	−1.09±0.07

aFold changes of cytokine genes were calculated by dividing the normalized signal intensities of genes in TNBS-treated colitis by those in mock.
^bFold changes of cytokine genes were calculated by dividing the normalized signal intensities of genes in EA-treated TNBS-induced colitis by those in untreated TNBS-induced colitis.